Tirzepatide

Dual GIP / GLP-1 receptor agonist

Tirzepatide is a single peptide that activates two incretin receptors at once — GIP and GLP-1. It was the first of the dual agonists to reach approval and reshaped expectations for what incretin-based research could achieve. Built from the natural GIP sequence, it represents a deliberate combining of two complementary signals into one molecule.